Publications

The following bibliography lists all of our publications in reverse chronological order.

Clark, D. F.; Go, E. P.; Toumi, M. L.; Desaire, H."Collision Induced Dissociation Products of Disulfide-Bonded Peptides: Ions Result from the Cleavage of More Than One Bond", J. Am. Soc. Mass Spectrometry (2011), 22, 492-498.

Go, E. P.; Hewawasam, G.; Liao, H.-X.; Chen, H.; Ping, L.-H.; Anderson, J. A.; Hua, D. C.; Haynes, B. F.; Desaire, H."Characterization of Glycosylation Profiles of HIV-1 Transmitted/Founder Envelopes by Mass Spectrometry", J. Virology (2011), 85, 8270-8284.

Go, E. P.; Hewawasam, G.; Ma, B.; Liao, H.; Haynes, B. F.; Desaire, H.; "Methods development for analysis of partially deglycosylated proteins and application to an HIV envelope protein vaccine candidate", Int. J. of Mass Spec., 305, (2011), 209-216.

Go, E. P.; Zhang, Y.; Menon, S.; Desaire, H."Analysis of the Disulfide Bond Arrangement of the HIV-1 Envelope Protein CON-S gp140 Delta CFI Shows Variability in the V1 and V2 Regions", J. Proteome Res. (2011), 10, 578-591.

Jo, S; Song, KC; Desaire, H; MacKerell, AD; Im, W, "Glycan Reader: Automated Sugar Identification and Simulation Preparation for Carbohydrates and Glycoproteins", J. Comp. Chem., 2011, 32 (14): 3135-3141.

Rebecchi, K.R.; Go, E.P.; Xu, L.; Woodin, C.L.; Mure, M.; Desaire, H. "A General Protease Digestion Procedure for Optimal Protein Sequence Coverage and Post-Translational Modifications Analysis of Recombinant Glycoproteins: Application to the Characterization of Human Lysyl Oxidase-like 2 Glycosylation". Anal. Chem. 2011, 83 (22): 8484-8491.

Toumi, M. L.; Desaire, H."Improving Mass Defect Filters for Human Proteins", J. Proteome Res. (2010), 9, 5492-5495.

Desaire H, Haynes BF, Go EP, Laio H, Sutherland LL, Chang Q, Zhang Y, Irungu J, Alam SM. "Glycosylation: an important factor in Env diversity". Retrovirol., (2009), 6, P378.

Go EP, Chang Q, Liao H-X, Sutherland LL, Alam SM, Haynes, BF, Desaire H. "Glcycosylation Site-Specific Analysis of Clade C HIV-1 Envelope", Proteins. J. Proteome Resch, (2009), 8, 4231-4242.

Toumi ML, Go EP, Desaire H." Development of fully functional proteins with novel glycosylation via enzymatic glycan trimming". J. Pharm. Sci. (2009), 98, 2581-2591.

Desaire H, Hua, D. "When can glycopeptides be assigned based solely on high resolution mass data?" Int. J. Mass Spec. (2009), In Press. Invited submission.

Rebecchi, KR, Wenke JL, Go EP, Desaire H." Label-Free Quantitation: A new glycoproteomics approach". J. Am. Soc. Mass Spectrom. (2009), 20, 1048-1059.

Bousfield GR, Butnev VY, Bidart J-M, Dalpathado DS, Irungu J, Desaire H. "Chromatofocusing fails to separate hFSH isoforms on the basis of glycan structure. Biochemistry", (2008), 47(6), 1708-1720.

Go, EP, Irungu J, Zhang Y, Dalpathado DS, Liao H-X, Sutherland LL, Alam SM, Haynes BF, Desaire H. "Glycosylation Site-Specific Analysis of HIV Envelope Proteins (JR-FL and CON-S) Reveals Major Differences in Glycosylation Site Occupancy, Glycoform Profiles, and Antigenic Epitopes’ Accessibility". J. Proteome Resch. (2008), 7(4), 1660-1674, Highlighted with a news feature in the journal. “Sweet Designs for an HIV vaccine” J. Proteome Resch.(2008), 7(4), 1372..

Zhang Y, Go EP, Desaire H. "Maximizing coverage of glycosylation heterogeneity in MALDI-MS analysis of glycoproteins with up to 27 glycosylation sites". Anal. Chem. (2008), 80(9), 3144-3158.

Dalpathado DS, Desaire H. "Glycopeptide analysis by mass sepectrometry". Analyst 133, 731-738, (2008). Invited review article –Top 10 most accessed in June, (2008).

Irungu J, Go EP, Zhang Y, Dalpathado DS, Liao HX, Haynes BF. Desaire H. "Comparison of LC/ESI-FTICR MS vs MALDI-TOF/TOF MS for glycopeptide analysis of a highly glycosylated protein: HIV Envelope glycoprotei"n. J. Am. Soc. Mass Spectrom. (2008), 19, 1209-1220.

Cruzado-Park ID, Alam M, Liao HX, Haynes B, Desaire H, Rabelli E, Coulter B, D'Costa S, Simonian MH, Ratnayake CK. "Carbohydrate analysis of HIV envelope glycoprotein". Clinical Immunol. (2007), 123, S38-S38.

Dalpathado, Dilusha S.; Chang, Qing; Burkett, Colleen M.; Bandu, Mary L.; Desaire, Heather. "Application of the statistical test of equivalent pathways (STEP) method to the triple quadrupole mass spectrometer". Rapid Com. in Mass Spec. (2007), 21(20), 3365-3372.

Go, Eden P.; Rebecchi, Kathryn R.; Dalpathado, Dilusha S.; Bandu, Mary L.; Zhang, Ying; Desaire, Heather. "GlycoPep DB: A Tool for Glycopeptide Analysis Using a "Smart Search". Analytical Chemistry (2007), 79(4), 1708-1713.

Irungu, Janet; Go, Eden P.; Dalpathado, Dilusha S.; Desaire, Heather. "Simplification of Mass Spectral Analysis of Acidic Glycopeptides Using GlycoPep ID". Analytical Chemistry (2007), 79(8), 3065-3074.

Bandu, Mary L.; Grubbs, Thomas; Kater, Marcus; Desaire, Heather. "Collision induced dissociation of alpha hydroxy acids: Evidence of an ion-neutral complex intermediate". Int. J. of Mass Spec. (2006), 251(1), 40-46.

Dalpathado, Dilusha S.; Irungu, Janet; Go, Eden P.; Butnev, Vladimir Y.; Norton, Katie; Bousfield, George R.; Desaire, Heather. "Comparative Glycomics of the Glycoprotein Follicle Stimulating Hormone: Glycopeptide Analysis of Isolates from Two Mammalian Species". Biochemistry (2006), 45(28), 8665-8673.

Zhang, Ying; Jiang, Hui; Go, Eden P.; Desaire, Heather. "Distinguishing Phosphorylation and Sulfation in Carbohydrates and Glycoproteins Using Ion-Pairing and Mass Spectrometry". Journal of the American Society for Mass Spectrometry (2006), 17(9), 1282-1288.

Yi, Lin; Dratter, Joe; Wang, Chao; Tunge, Jon A.; Desaire, Heather. "Identification of sulfation sites of metabolites and prediction of the compounds' biological effects". Analytical and Bioanalytical Chemistry (2006), 386(3), 666-674.

Irungu, Janet; Dalpathado, Dilusha S.; Go, Eden P.; Jiang, Hui; Ha, Hy-Vy; Bousfield, George R.; Desaire, Heather. "Method for Characterizing Sulfated Glycoproteins in a Glycosylation Site-Specific Fashion, Using Ion Pairing and Tandem Mass Spectrometry". Analytical Chemistry (2006), 78(4), 1181-1190.

Bandu, Mary L.; Desaire, Heather." The STEP method (statistical test of equivalent pathways): application to pharmaceuticals". Analyst (2006), 131(2), 268-274.

Jiang, Hui; Irungu, Janet; Desaire, Heather. "Enhanced detection of sulfated glycosylation sites in glycoproteins". Journal of the American Society for Mass Spectrometry (2005), 16(3), 340-348.

Yi, Lin; Bandu, Mary L.; Desaire, Heather. "Identifying lactone hydrolysis in pharmaceuticals. a tool for metabolite structural characterization". Analytical Chemistry (2005), 77(20), 6655-6663.

Zhang, Ying; Go, Eden P.; Jiang, Hui; Desaire, Heather. "A Novel Mass Spectrometric Method to Distinguish Isobaric Monosaccharides that are Phosphorylated or Sulfated Using Ion-Pairing Reagents". Journal of the American Society for Mass Spectrometry (2005), 16(11), 1827-1839.

Dalpathado, Dilusha S.; Jiang, Hui; Kater, Marcus A.; Desaire, Heather. "Reductive amination of carbohydrates using NaBH(OAc)3". Analytical and Bioanalytical Chemistry (2005), 381(6), 1130-1137.

Bandu, Mary L.; Wilson, Jonathan; Vachet, Richard W.; Dalpathado, Dilusha S.; Desaire, Heather. "STEP (Statistical Test of Equivalent Pathways) Analysis: A Mass Spectrometric Method for Carbohydrates and Peptides". Analytical Chemistry (2005), 77(18), 5886-5893.

Jiang, Hui; Desaire, Heather; Butnev, Vladimir Y.; Bousfield, George R. "Glycoprotein profiling by electrospray mass spectrometry". Journal of the American Society for Mass Spectrometry (2004), 15(5), 750-758.

Bandu, Mary L.; Watkins, Kathryn R.; Bretthauer, Melinda L.; Moore, Christopher A.; Desaire, Heather. "Prediction of MS/MS Data. 1. a focus on pharmaceuticals containing carboxylic acids". Analytical Chemistry (2004), 76(6), 1746-1753.

Desaire, Heather; Leavell, Michael D.; Leary, Julie A. "Solvent Effects in Tandem Mass Spectrometry: Mechanistic Studies Indicating How a Change in Solvent Conditions and pH Can Dramatically Alter CID Spectra". Journal of Organic Chemistry (2002), 67(11), 3693-3699.

Desaire, Heather Renee. "Characterization of isomeric carbohydrates using metal coordination, enzymatic digestion, and tandem mass spectrometry". (2001), 268

Desaire, H.; Leary, J. A. "The effects of coordination number and ligand size on the gas phase dissociation and stereochemical differentiation of cobalt-coordinated monosaccharides". Int. J. of Mass Spec. (2001), 209(2-3), 171-184.

Desaire, Heather; Sirich, Tammy L.; Leary, Julie A." Evidence of block and randomly sequenced chondroitin polysaccharides: Sequential enzymatic digestion and quantification using ion trap tandem mass spectrometry". Analytical Chemistry (2001), 73(15), 3513-3520.

Desaire, H.; Beyer, M. K.; Leary, J. A. "Molecular orbital considerations in probing the stereoselective dissociation of cobalt-coordinated hexosamine monosaccharides". Journal of the American Society for Mass Spectrometry (2001), 12(5), 517-527.

Ge, Xue; Sirich, Tammy L.; Beyer, Martin K.; Desaire, Heather; Leary, Julie A. "A strategy for the determination of enzyme kinetics using electrospray ionization with an ion trap mass spectrometer". Analytical Chemistry (2001), 73(21), 5078-5082.

Cancilla, Mark T.; Gaucher, Sara P.; Desaire, Heather; Leary, Julie A. "Combined Partial Acid Hydrolysis and Electrospray Ionization-Mass Spectrometry for the Structural Determination of Oligosaccharides". Analytical Chemistry (2000), 72(13), 2901-2907.

Desaire, H.; Leary, J. A. "Detection and quantification of the sulfated disaccharides in chondroitin sulfate by electrospray tandem mass spectrometry". Journal of the American Society for Mass Spectrometry (2000), i(10), 916-920.

Desaire, H.; Leary, J. A. "Utilization of MS3 spectra for the multicomponent quantification of diastereomeric N-acetylhexosamines". Journal of the American Society for Mass Spectrometry (2000), 11(12), 1086-1094.

Desaire, Heather; Leary, Julie A. "Differentiation of Diastereomeric N-Acetylhexosamine Monosaccharides Using Ion Trap Tandem Mass Spectrometry". Analytical Chemistry (1999), 71(10), 1997-2002.

Desaire, Heather; Leary, Julie A. "Multicomponent quantification of diastereomeric hexosamine monosaccharides using ion trap tandem mass spectrometry". Analytical Chemistry (1999), 71(19), 4142-4147.

Baker, Shenda M.; Danzer, Joseph; Desaire, Heather; Credo, Grace; Flitton, Rebecca. "Alcohol Chain Length and Mole Fraction Dependence of the Stability of Tetrakis(cumylphenoxy)phthalocyanine and Alcohol Langmuir Films". Langmuir (1998), 14(18), 5267-5273.


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